Stable_Isotope

Stable Isotope:
Isotopes are the atoms of the same element that differ in atomic mass, due to difference in the number of neutrons contained in the atom’s nuclei. Isotopes are categorized into two specific types: stable and unstable. For example, the three most abundant isotopes of the Hydrogen are Hydrogen-1 (1H), which contains 1 proton, 1 electron, and 1 neutron; Hydrogen-2 (2H or D), which also has 1 proton and electron, but 2 neutron; and Hydrogen-3 (3H or T) which also contains 1 proton and 1 electron, but 3 neutrons. Having too few or too many neutrons compared to protons causes some isotopes such as 3H to be unstable. These unstable radioisotopes will decay to stable products.

Other isotopes such as 1H and 2H do not decay, because their particular combinations of neutrons are stable. These kinds of isotopes are known as stable isotopes. The relative abundance of stable isotopes in the same compounds from different sources could be different due to the thermodynamic and kinetic effects during chemical and physical process. It can be measured experimentally (isotope analysis), yielding an isotope ratio that is used as a research tool. As a result, stable isotopes have been founding several applications in variety of research areas including the following fields of science:

Chemistry

  • NMR solvent
  • Kinetic and mechanism investigation
  • Labeled compounds
  • Internal standards

 

Medical science

  • Positron Emission Tomography
  • Magnetic Resonance Imaging
  • Magnetic Resonance spectroscopy
  • Diagnosis of disease
  • To understand metabolic pathways in humans
  • To measure the rate of a related process

 

Pharmacy

  • To study the metabolites of drugs
  • Drug discovery
  • Drug delivery
  • To determine the pharmacokinetic profile

 

Hydrology

  • To determine the age of ice or snow, and water resource
  • To indicate the conditions of the climate in the past
  • To distinguish groundwater flow and base-flow from stream-flow in the field of catchment hydrology
  • To determine the different layers of deep water
  • To determine mixing and flow paths of water within a system

 

Forensic sciences

  • Determining whether samples of chemically similar substances such as drugs, explosives, fibers, paints, inks, tapes or adhesives may share a common source or history
  • Distinguishing counterfeit products ( e. g pharmaceuticals) from genuine materials
  • Comparing putative reactants with contraband products
  • Environmental Forensic and monitoring
    • Identifying the source of pollutants such as oil spills
    • Monitoring atmospheric gases to Distinguish between natural and anthropogenic sources
    • Climate studies
    • Water cycle research
  • Food authenticity and traceability
    • establishing the geographic authenticity of foodstuffs
    • Identifying the adulteration of food with cheaper ingredients
  • wildlife Forensics
    • geochemistry and geology
    • establishing the extent and temperature of post – burial alteration of rocks
    • provenancing of clasts
    • identifying the source of water sample
  • palaeoclimatology
  • palaeocology

 

Biological science

  • Ecology
    • To understand processes of soil organic matter formation
    • photosynthetic pathways
    • food webs
    • ecohydrology
    • nutrient cycling
  • Human and plant physiology
  • Human provenancing
  • Metabolic studies
  • Sport medicine and Anti doping control
  • Toxicology
  • Distinguishing endogenous versus exogenous bio-chemicals

 

Environmental Science

  • To determine the source of pollutants
  • To follow whole ecosystem element cycling
  • To understand the effects of pollution in both terrestrial and aquatic environments
  • To study extreme systems such as hydrothermal vents
  • To follow migrating organisms

 

Electronic and communication industry

Animal husbandry

Agriculture

Astronomy

Geology

Products & Services

NMR Solvents

NMR solvents are another form (called isotopologue) of organic solvents in which the hydrogen atoms ("H") are replaced with deuterium (heavy hydrogen) isotope ("D"). NMR solvents are common solvent used in NMR spectroscopy.

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Stable Isotope Labeled Compound

Over the recent years application of Stable Isotope Labeled Compound has soared through the variety of research areas, including the following ones:
1. Magnetic Resonance Imaging and Magnetic Resonance spectroscopy (MRI/MRS), NMR, PET

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Doubly Labeled Water

Doubly labeled water (DLW) is water in which both the hydrogen and the oxygen have been replaced with known concentration of deuterium and oxygen-18, for tracing study.

Laboratories

Mesbah Energy Company analysis section contains two modern and equipped labs, including Water and Stable Isotopic analysis labs.

 

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